A woman whose ‘world was blown apart’ after a cancer diagnosis nearly 10 years ago will be running the London Marathon in celebration of her life.

But Lois Rennie, 43, from Coleshill Lane, Amersham, is also running in memory of those close to her who have both suffered and lost their lives to the disease.

Tragically, Mrs Rennie lost her mother, Pat, to lung cancer 20 years ago and her brother in law Bob to an aggressive brain tumour in 2010.

She said: “Being without a mum is the toughest job there is – far tougher than anything the world of corporate sales can throw at me. I think of her every day and desperately wish I could share my life and my own family with her.”

Speaking about Bob she added: “A baker by trade, Bob was one of the most laid back, good humoured men you could ever meet. Diagnosed with an aggressive brain tumour, three months later he too lost his fight, aged 44.”

Mother of two Mrs Rennie said she first tried running during her own chemotherapy treatment, as it gave her ‘something to focus on,’ and she decribes herself as ‘more of an occasional shuffler than a dedicated runner’.

Her determination to finish means she ‘will be crossing that finish line in April, even if it’s on my hands and knees, and knowing I have the support of friends, family and colleagues will motivate me in the darkest hours’, despite suffering from a recent hip injury.

Mrs Rennie’s family owned Insport, the sports shop in Hill Avenue, Amersham, from the 1970s to the 1990s. Her mother worked there as well as running Lady Golf, which later became Leisure Lady and is now HTR Clothing.

She added: “It’s a cause close to my heart and an important thing to raise as much money for as possible.”

Speaking about the marathon she said: “I really can’t wait. I feel really emotional about it. It’s going to mean an awful lot. I’m just aiming to enjoy the day and have a fantastic experience - it will be quite an achievement.”

She added: “People say the feeling of having everybody shouting your name and complete strangers supporting you and urging you on will be overwhelming.”

And she said she just wants to ‘make my family and friends proud of me’ while raising as much money as she can.

Mrs Rennie’s fundraising page can be found at https://www.justgiving.com/Lois-Rennie.